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Pediatrician by Tio Manolo

Sunday, March 22, 2026 Edition XXI
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This Week in Pediatrics

Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips

ByPatrick Campbell · March 16th 2026 · A phase 3 trial shows that lebrikizumab improves skin clearance and itch in infants and children with moderate to severe atopic dermatitis.

It's not just vaccines — parents are refusing other routine preventive care for newborns

“When you look at a child who’s innocent and vulnerable — and a simple intervention that’s been done since 1961 is refused — knowing that baby’s going out into the world is super worrisome to me,” said Patterson, who’s been a pediatrician for nearly three decades. ... Doctors acr...

Recent Reports from University of Michigan Medical School Highlight Findings in Hospital Pediatrics (Insurance Coverage Disruption Among Children and Caregivers After Pediatric Hospitalization): Pediatrics - Hospital Pediatrics - Insurance News | InsuranceNewsNet

2026 MAR 18-- By a News Reporter-Staff ... in Ann Arbor, Michigan, by NewsRx journalists, research stated,“ Health events may disrupt insurance ......

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Research of the Day

Naturalistic Developmental Behavioral Interventions Before Age 2: RCT

This RCT provided Naturalistic Developmental Behavioral Interventions (NDBI) to infants showing early autism markers at 12-18 months. Early intervention significantly improved social communication outcomes at age 3.

Key findings: (1) 40% of intervention group no longer met ASD criteria at age 3; (2) Greater gains when started before 15 months; (3) Parent-mediated strategies effective when coached by professionals.

🩺 What this means for your practice:

Refer promptly when developmental concerns arise—don't wait for definitive diagnosis. Early intervention can meaningfully change trajectories. Coach parents to implement strategies in daily routines.

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Popular Beliefs

Vaccines cause autism

What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.

Cold weather causes colds

What the evidence shows: Colds are caused by viruses, not cold temperatures. The association exists because people spend more time indoors in close proximity during winter, facilitating viral transmission. Additionally, dry indoor air may impair mucosal barriers. Hand hygiene and avoiding sick contacts are the real prevention strategies.

Children outgrow ADHD

What the evidence shows: While symptoms often change with age, approximately 60% of children with ADHD continue to have symptoms into adulthood. Hyperactivity typically decreases, but inattention and impulsivity often persist. Ongoing monitoring and treatment adjustment is important across the lifespan.

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Behaviors

Bedtime Routine Consistency and Child Behavior: Observational Study

This analysis of 5,000 parent surveys examined the relationship between bedtime routine consistency and daytime behavior. Children with consistent, calming bedtime routines had fewer behavioral problems and better emotional regulation.

Key findings: (1) Inconsistent routines associated with 2x behavioral difficulties; (2) Routines including reading showed strongest effects; (3) Benefits seen across all age groups studied (2-10 years).

🩺 What this means for your practice:

Bedtime routines matter for more than just sleep—they shape behavior and emotional regulation. Help families develop simple, consistent routines even during busy periods.

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Genetics

CRISPR Gene Editing for Sickle Cell Disease: Long-Term Follow-Up

Long-term data from CRISPR-edited sickle cell patients shows durable remission of vaso-occlusive crises in 95% of treated patients at 4-year follow-up. The one-time treatment has transformed the disease trajectory for participants.

Key findings: (1) No vaso-occlusive crises in 95% of patients; (2) Hemoglobin levels maintained in normal range; (3) No off-target editing effects detected. Access and affordability remain challenges.

🩺 What this means for your practice:

Curative therapy for sickle cell disease is now reality, though access barriers remain. Stay informed about treatment centers and insurance coverage in your area. Early referral for evaluation is appropriate.

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Did You Know? Numbers & Statistics

10.4%
Births occurring before 37 weeks gestation
CDC NCHS, 2024
5.4M
Children under 18 with asthma in the United States
CDC, 2024
38%
Children 6mo-17y completed COVID-19 primary series
CDC, 2024
100K
People in the US with sickle cell disease
CDC, 2024