This Week in Pediatrics
Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips
ByPatrick Campbell · March 16th 2026 · A phase 3 trial shows that lebrikizumab improves skin clearance and itch in infants and children with moderate to severe atopic dermatitis.
The American Academy of Pediatrics Has Its Own 2026 Vaccine Schedule—Here’s What Changed
The updated 2026 vaccine schedule from the AAP recommends immunization from 18 different diseases, including polio, measles, flu, COVID, and more. The AAP’s schedule has been endorsed by 12 medical and health ...
The State of US Vaccine Policy: Special Edition — Mar 17, 2026 | CIDRAP
About 92% of confirmed 2026 measles cases are among people who were unvaccinated or had unknown vaccination status. The stakes of getting this wrong are not abstract. In February, the New England Journal of Medicine · published a case report ...
Research of the Day
School Start Times and Adolescent Mental Health: A Natural Experiment
This natural experiment followed 50,000 high school students before and after a district-wide shift to later school start times (8:30am vs 7:15am). Students gained an average of 45 minutes of sleep per night and showed significant improvements in mental health markers over the 2-year study period.
Key findings: (1) 27% reduction in depressive symptoms; (2) 34% decrease in suicidal ideation reports; (3) Improved academic performance and attendance. Effects were most pronounced in students getting 8+ hours of sleep.
These data support advocating for developmentally appropriate school start times. Middle and high school students need 8-10 hours of sleep—counsel families on sleep hygiene and the importance of adequate rest for mental health.
Popular Beliefs
Too many vaccines overwhelm a child's immune system
What the evidence shows: Children's immune systems handle vastly more antigens daily from the environment than from vaccines. Today's vaccines contain far fewer antigens than older versions despite protecting against more diseases. Studies show no increased infection rates in vaccinated children—vaccines strengthen, not weaken, immunity.
Warm milk helps children sleep
What the evidence shows: While milk contains tryptophan (a sleep-promoting amino acid), the amount is modest. Any sleep benefit likely comes from the comforting ritual and warmth rather than pharmacologic effect. A consistent bedtime routine matters more than any single component.
ADD/ADHD is caused by poor parenting or too much sugar
What the evidence shows: ADHD has strong genetic and neurobiological components. While environment can influence symptom severity, poor parenting and diet do not cause ADHD. Evidence-based treatments include behavioral therapy and, when appropriate, medication. Blaming parents is harmful and delays effective intervention.
Behaviors
Early Pet Exposure and Immune Development: Birth Cohort Study
This birth cohort followed 1,200 children from birth to age 5, comparing immune development and allergy rates in homes with and without pets. Early pet exposure was associated with reduced allergy risk and altered gut microbiome.
Key findings: (1) 30% lower allergic sensitization with dog exposure in first year; (2) Cat exposure showed similar but smaller effects; (3) Microbiome diversity increased in pet-exposed children.
Reassure families that pet exposure during infancy may actually protect against allergies. For families without pets, don't specifically recommend getting one, but dispel the myth that pets must be removed to prevent allergies.
Genetics
Gene Therapy for Phenylketonuria: Phase 2 Trial Results
Phase 2 trial results of a novel gene therapy for PKU show sustained reduction in phenylalanine levels, potentially eliminating the need for restrictive diet in some patients. Single-dose treatment showed effects lasting 2+ years in most participants.
Key findings: (1) 70% of participants achieved normal Phe levels without diet; (2) No serious adverse events; (3) Quality of life significantly improved with dietary liberalization.
Gene therapy is expanding beyond rare diseases to common metabolic conditions. For PKU families, inform them of emerging options while continuing to support dietary adherence.