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Pediatrician by Tio Manolo

Sunday, March 29, 2026 Edition XXVIII
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This Week in Pediatrics

Imagine Pediatrics Releases First Annual Impact Report Demonstrating Proven Outcomes in Pediatric Value-Based Care

Report reveals how 24/7 integrated virtual and in-home care helps children with special health care needs have more safe days at home · NASHVILLE, Tenn., March 26, 2026 /PRNewswire/ -- New data from · Imagine Pediatrics shows that a 24/7 ...

Therapeutic Drug Monitoring Use Varies Widely in Pediatric Rheumatology

Researchers sent a survey to 412 US and Canadian pediatric rheumatology providers with 65 questions about their TDM practices for adalimumab, infliximab, azathioprine, cyclosporine, hydroxychloroquine, mycophenolate mofetil (MMF), and rituximab.

2026 - Association of Pediatric Program Directors

... In 2026, the APPD Annual Spring Meeting will be held April 14-17 in Denver, Colorado. The APPD spring meeting provides pediatric program educators and leaders with the opportunity to network and learn what’s new in medical education curriculum.

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Research of the Day

Universal Depression Screening in Adolescents: Implementation and Outcomes

This pragmatic trial implemented universal depression screening using PHQ-9 Modified for Adolescents across 50 primary care practices. Universal screening identified 3x more cases of moderate-to-severe depression compared to targeted screening.

Key findings: (1) 18% of screened adolescents had positive screens requiring follow-up; (2) Early identification led to 40% increase in mental health referrals; (3) False positive rate acceptable at 12%.

🩺 What this means for your practice:

Implement annual depression screening for all patients 12-21 years. Establish referral pathways and follow-up protocols. Address barriers to mental health access in your community.

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Popular Beliefs

Cold weather causes colds

What the evidence shows: Colds are caused by viruses, not cold temperatures. The association exists because people spend more time indoors in close proximity during winter, facilitating viral transmission. Additionally, dry indoor air may impair mucosal barriers. Hand hygiene and avoiding sick contacts are the real prevention strategies.

Shaving makes hair grow back thicker and darker

What the evidence shows: Shaving removes hair at the skin surface, leaving a blunt tip that may feel coarser as it grows out. However, it does not affect hair thickness, color, or growth rate. This is an optical illusion from the blunt vs. tapered hair shaft.

Vaccines cause autism

What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.

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Behaviors

Musical Training and Brain Development in Children: Longitudinal Neuroimaging Study

This 3-year study compared brain development in children receiving musical instrument training versus those doing sports or no organized activity. Music training was associated with enhanced auditory processing, motor coordination, and executive function networks.

Key findings: (1) Increased cortical thickness in auditory and motor regions; (2) Better performance on working memory and attention tasks; (3) Benefits correlated with practice duration.

🩺 What this means for your practice:

Music education offers cognitive benefits beyond artistic development. When families ask about extracurriculars, mention music as a brain-healthy option. Benefits appear even with modest practice time.

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Genetics

CFTR Modulator Therapy in Young Children: Expansion to Additional Mutations

New clinical trial data supports expanding CFTR modulator therapy to children as young as 1 year with various CFTR mutations. Early treatment initiation shows benefits in lung function preservation and nutritional status, with excellent safety profile.

Key findings: (1) 85% of CF patients now eligible for modulator therapy; (2) Early treatment prevents rather than reverses lung damage; (3) Growth parameters improved in treated toddlers.

🩺 What this means for your practice:

Refer CF patients promptly for genetic classification and modulator eligibility assessment. The treatment landscape has transformed—many children can now expect near-normal life expectancy with appropriate therapy.

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Did You Know? Numbers & Statistics

57%
Children 6mo-17y vaccinated against influenza
CDC, 2024
100K
People in the US with sickle cell disease
CDC, 2024
13%
Children diagnosed with eczema/atopic dermatitis
CDC NHIS, 2024
10.4%
Births occurring before 37 weeks gestation
CDC NCHS, 2024