This Week in Pediatrics
Extensive Testing Offers Little Diagnostic Value in Suspected Pediatric Acute-Onset Neuropsychiatric Syndrome
Broad laboratory testing for children with suspected pediatric acute-onset neuropsychiatric syndrome (PANS) may neither distinguish PANS from similar psychiatric conditions nor reliably identify underlying medical causes, according to new data published in JAMA Network Open.
Europe Moves to Broader Pediatric Pneumonia Protection
At its March 2026 meeting, the European Medicines Agency’s Committee for Medicinal Products for Human Use issued a positive opinion recommending the expanded use of Capvaxive (pneumococcal 21-valent conjugate vaccine, Merck Sharp & Dohme B.V.) to ...
A deadly bacterial disease is returning, doctors warn, as vaccination rates fall
Kathryn Edwards, a vaccine safety expert and professor of pediatrics at Vanderbilt University Medical Center in Nashville, Tennessee, said her colleagues recently treated two cases of Hib-related meningitis. Previously, Vanderbilt hadn’t had such a case for “a number of years,” s...
Research of the Day
Inhaled Corticosteroid Adherence in Minority Children: Community Health Worker Intervention
This RCT evaluated community health worker (CHW) home visits to improve inhaled corticosteroid adherence in 400 minority children with persistent asthma. CHW intervention nearly doubled medication adherence rates.
Key findings: (1) Adherence improved from 45% to 82% in intervention group; (2) 50% reduction in asthma-related ED visits; (3) Culturally tailored education more effective than standard approach.
Consider CHW programs or similar support for families struggling with asthma medication adherence. Address social determinants and provide culturally appropriate education.
Popular Beliefs
Wait 30 minutes after eating before swimming
What the evidence shows: There's no evidence that swimming after eating causes cramps or drowning. While digestion diverts some blood flow to the gut, it doesn't impair swimming ability in normal circumstances. Common-sense supervision is always important regardless of meal timing.
Cracking knuckles causes arthritis
What the evidence shows: Studies comparing habitual knuckle-crackers to non-crackers found no increased arthritis risk. The cracking sound is from gas bubble release in synovial fluid. The main consequence may be reduced grip strength and annoyed family members.
Green mucus means bacterial infection requiring antibiotics
What the evidence shows: Mucus color changes naturally during viral infections and does not reliably distinguish viral from bacterial causes. Green/yellow mucus indicates immune cell activity, which occurs in both viral and bacterial infections. Antibiotics should be prescribed based on clinical criteria, not mucus color.
Behaviors
Sleep Schedule Consistency and ADHD Symptoms: Intervention Study
This intervention study examined whether consistent sleep schedules improved ADHD symptoms in 150 children ages 6-12. Families implemented strict bed/wake times for 8 weeks while tracking symptoms and sleep.
Key findings: (1) Consistent sleep reduced inattention symptoms by 25%; (2) Bedtime resistance decreased significantly; (3) Effects comparable to some medication responses. Weekend sleep consistency was particularly important.
Before escalating ADHD treatment, optimize sleep hygiene. Consistent bed/wake times (including weekends) can meaningfully improve symptoms. This is a low-risk intervention all families can implement.
Genetics
Genetic Predictors of Peanut Allergy Persistence
Genome-wide association study identifies genetic variants associated with peanut allergy persistence versus resolution. Children with certain variants are more likely to outgrow their allergy, informing timing of oral food challenges.
Key findings: (1) 4 genetic variants strongly associated with persistence; (2) Genetic testing could reduce unnecessary avoidance and challenges; (3) Environmental factors remain important in allergy development.
Genetic testing may soon help predict which children will outgrow allergies. For now, continue regular reassessment with IgE testing and oral challenges as clinically indicated.