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Pediatrician by Tio Manolo

Sunday, April 5, 2026 Edition XXXV
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This Week in Pediatrics

Q1 2026 recap: Top videos in pediatric care | Contemporary Pediatrics

The SMART trial serves as a pivotal study to bridge efficacy data from healthy infants, established in the CLEVER trial, to those with complex medical needs. Because clesrovimab is designed to target the viral F protein without interacting with the host, clinical protection is de...

Pediatrics - Medscape

Your one-stop resource for medical news, clinical reference, and education. Sign up for FREE ... The ‘Peanut Panic’ was a self-fulfilling prophecy. Dr Christopher Labos discusses the pediatric food allergy epidemic and how we’re finally reversing the trend.

Q2 2026 preview: 4 FDA decisions to watch in pediatric care | Contemporary Pediatrics

1. Inhaled Insulin (Afrezza; MannKind Corporation)1 Date: May 29, 2026 Indication: To improve glycemic control in children and adolescents aged 4 to 17 years living with type 1 or type 2 diabetes.

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Research of the Day

Adolescent Vaping Cessation: Randomized Trial of Behavioral Interventions

This RCT compared three vaping cessation approaches in 1,200 adolescents: text-based support, in-person counseling, and combined intervention. Combined approach showed highest quit rates at 6-month follow-up.

Key findings: (1) 28% quit rate with combined intervention vs 15% text-only; (2) Nicotine dependence level predicted quit success; (3) Most adolescents wanted to quit but lacked support resources.

🩺 What this means for your practice:

Screen for vaping at every adolescent visit. Offer cessation resources proactively—most teens want to quit. Combine counseling with digital support for best outcomes.

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Popular Beliefs

Children outgrow ADHD

What the evidence shows: While symptoms often change with age, approximately 60% of children with ADHD continue to have symptoms into adulthood. Hyperactivity typically decreases, but inattention and impulsivity often persist. Ongoing monitoring and treatment adjustment is important across the lifespan.

Remove ticks with a lit match or petroleum jelly

What the evidence shows: These methods can cause the tick to regurgitate into the wound, increasing disease transmission risk. Use fine-tipped tweezers to grasp the tick close to the skin and pull upward with steady pressure. Save the tick for identification if possible.

Too many vaccines overwhelm a child's immune system

What the evidence shows: Children's immune systems handle vastly more antigens daily from the environment than from vaccines. Today's vaccines contain far fewer antigens than older versions despite protecting against more diseases. Studies show no increased infection rates in vaccinated children—vaccines strengthen, not weaken, immunity.

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Behaviors

Growth Mindset and Academic Resilience in Middle School

This school-based intervention taught growth mindset principles to 4,000 middle schoolers. Students who internalized growth mindset showed improved grades, greater persistence, and reduced anxiety around academic challenges.

Key findings: (1) 0.3 GPA improvement in intervention group; (2) 25% reduction in test anxiety; (3) Effects largest for initially low-performing students. Teacher reinforcement of messages enhanced effects.

🩺 What this means for your practice:

Praise effort over ability when discussing academics with patients. Encourage families to use growth mindset language. Struggle is part of learning, not a sign of inability.

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Genetics

Gene Therapy Shows Promise for Spinal Muscular Atrophy Type 1

Long-term follow-up data from the Phase 3 clinical trial of onasemnogene abeparvovec gene therapy reveals sustained motor milestone achievements in children with SMA Type 1 treated before 6 months of age. At 5-year follow-up, 94% of early-treated patients maintained the ability to sit independently, and 68% achieved independent walking—outcomes historically unprecedented in untreated SMA Type 1.

The study also reports on safety outcomes, with no new treatment-related serious adverse events emerging after year 2. These results strengthen the case for newborn screening and early intervention in SMA.

🩺 What this means for your practice:

This data reinforces the critical importance of early diagnosis and treatment in SMA. Support newborn screening initiatives in your state. For families with SMA history, discuss carrier testing and ensure rapid referral to neuromuscular specialists if symptoms arise.

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Did You Know? Numbers & Statistics

13%
Children diagnosed with eczema/atopic dermatitis
CDC NHIS, 2024
61%
Adolescents 13-17 with complete HPV vaccination
CDC NIS-Teen, 2024
500K
Children ages 1-5 with elevated blood lead levels
CDC, 2024
13.2
Births per 1,000 females ages 15-19 (historic low)
CDC NCHS, 2024