This Week in Pediatrics
Q2 2026 Preview: 6 FDA Decisions to Watch | HCPLive
Two-year DUPLEX data published in the New England Journal of Medicine showed significant proteinuria reduction, higher remission rates, and a lower rate of end-stage kidney disease compared to active control irbesartan.
UC Davis Pediatric Mobile Clinic brings specialty care to children and families across Sacramento region
With early success and strong community demand, UC Davis Health plans to continue expanding the Pediatric Mobile Clinic model, bridging health care, education and community to support the health of children and families. “Our findings show mobile clinics can close longstanding ga...
FDA seeks permanent future for rare pediatric priority review vouchers - Pharmaceutical Technology
The document contained justifications for the 3.3% budget rise compared to fiscal year 2026, as well as several legislative shifts. ... The gold standard of business intelligence.
Research of the Day
Family-Based Treatment for Childhood Obesity: 5-Year Outcomes
This long-term follow-up evaluated family-based behavioral treatment (FBT) for childhood obesity. Children who received FBT maintained healthier BMI trajectories compared to usual care, with parental involvement being key to sustained success.
Key findings: (1) 25% greater BMI reduction maintained at 5 years; (2) Parental BMI change correlated with child outcomes; (3) Maintenance sessions improved long-term success.
Engage the whole family in obesity treatment—target the child alone is less effective. Focus on sustainable lifestyle changes, address family habits, and plan for ongoing support.
Popular Beliefs
Teething causes high fevers and diarrhea
What the evidence shows: While teething may cause mild symptoms (gum irritation, drooling, slight temperature elevation), it does not cause high fever (>102°F/38.9°C) or diarrhea. These symptoms should prompt evaluation for other causes. Attributing significant illness to teething may delay diagnosis of serious conditions.
Letting babies walk early causes bowlegs
What the evidence shows: There is no evidence that early walking causes bowlegs. Most infants have some degree of bowing that typically resolves by age 3-4. Pathologic bowing has other causes (Blount disease, rickets). Encourage normal motor development and monitor for asymmetric or progressive bowing.
Vaccines cause autism
What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.
Behaviors
Secondhand Smoke Exposure and Cognitive Development: Cohort Study
This cohort study measured cotinine levels and cognitive outcomes in 2,000 children at multiple time points. Even low-level secondhand smoke exposure was associated with measurable effects on attention and working memory.
Key findings: (1) Detectable cotinine associated with 5-point IQ difference; (2) Higher rates of learning difficulties; (3) No safe threshold identified—any exposure had measurable effects.
Screen for smoke exposure at well visits. Counsel caregivers that even 'smoking outside' may not fully protect children. Connect families with smoking cessation resources.
Genetics
Polygenic Risk Scores and ADHD: Clinical Utility Analysis
Large GWAS analysis demonstrates polygenic risk scores for ADHD have limited current clinical utility for diagnosis but may help identify children at risk for severe or persistent symptoms. Environmental factors remain critically important.
Key findings: (1) Polygenic scores explain ~10% of ADHD variance; (2) Higher scores associated with earlier onset and persistence; (3) Not useful as diagnostic test—clinical evaluation remains gold standard.
Genetics is one piece of the ADHD puzzle but doesn't replace clinical assessment. Avoid overinterpreting direct-to-consumer genetic tests. Family history remains the most useful genetic 'test' for ADHD risk.