This Week in Pediatrics
Leading with heart: Juan Salazar’s mission to advance pediatric health care for all children - Vanderbilt Health News
I wanted to devote my career to infectious diseases in children, with a lot of emphasis on pediatric AIDS. A: So, the good news is that with the prevention of mother-to-infant transmission of HIV, plus the benefit of antiretroviral medications, fewer kids became infected with HIV...
Cedars-Sinai Guerin Children’s Experts Available for Interviews During PAS 2026 | Newswise
Newswise — LOS ANGELES (April 21, 2026) -- Cedars-Sinai Guerin Children’s experts are presenting advances in research and leading hands-on patient care workshops at the Pediatric Academic Societies (PAS) annual meeting, April 24–27 in Boston.
Dr. Yvonne Fanous honored with Dr. Leonard L. Bailey Outstanding Clinician at 2026 Children’s Hospital Gala | News
Yvonne Fanous, MD, a pediatric allergist and immunologist at Loma Linda University Children’s Hospital, has been named the recipient of the 2026 Dr. Leonard L. Bailey Outstanding Clinician Award, an honor recognizing her more than four decades ...
Research of the Day
Delayed Epinephrine Administration in Pediatric Anaphylaxis: Multi-Center Analysis
This multi-center retrospective study analyzed 2,800 pediatric anaphylaxis cases across 12 children's hospitals. Delayed epinephrine administration (>15 minutes from symptom onset) occurred in 42% of cases and was associated with increased risk of severe outcomes and biphasic reactions.
Key findings: (1) Delayed epinephrine associated with 3.2x increased odds of hospitalization; (2) Food-induced reactions most likely to have delayed treatment; (3) Many families cited fear of injection or uncertainty about symptoms as reasons for delay.
Reinforce epinephrine-first messaging for anaphylaxis. Ensure families can recognize symptoms and use auto-injectors confidently. Consider demonstration at every visit for patients with prescribed epinephrine.
Popular Beliefs
The flu shot can give you the flu
What the evidence shows: Flu vaccines contain inactivated virus or viral proteins that cannot cause influenza infection. Some people experience mild side effects (sore arm, low-grade fever) that mimic illness. It takes 2 weeks for protection to develop, so some may get infected before the vaccine works.
Green mucus means bacterial infection requiring antibiotics
What the evidence shows: Mucus color changes naturally during viral infections and does not reliably distinguish viral from bacterial causes. Green/yellow mucus indicates immune cell activity, which occurs in both viral and bacterial infections. Antibiotics should be prescribed based on clinical criteria, not mucus color.
Organic food is significantly more nutritious
What the evidence shows: Organic foods have lower pesticide residues, but studies show minimal nutritional differences compared to conventional foods. What matters most for health is eating a variety of fruits and vegetables, whether organic or conventional.
Behaviors
Secondhand Smoke Exposure and Cognitive Development: Cohort Study
This cohort study measured cotinine levels and cognitive outcomes in 2,000 children at multiple time points. Even low-level secondhand smoke exposure was associated with measurable effects on attention and working memory.
Key findings: (1) Detectable cotinine associated with 5-point IQ difference; (2) Higher rates of learning difficulties; (3) No safe threshold identified—any exposure had measurable effects.
Screen for smoke exposure at well visits. Counsel caregivers that even 'smoking outside' may not fully protect children. Connect families with smoking cessation resources.
Genetics
Polygenic Risk Scores and ADHD: Clinical Utility Analysis
Large GWAS analysis demonstrates polygenic risk scores for ADHD have limited current clinical utility for diagnosis but may help identify children at risk for severe or persistent symptoms. Environmental factors remain critically important.
Key findings: (1) Polygenic scores explain ~10% of ADHD variance; (2) Higher scores associated with earlier onset and persistence; (3) Not useful as diagnostic test—clinical evaluation remains gold standard.
Genetics is one piece of the ADHD puzzle but doesn't replace clinical assessment. Avoid overinterpreting direct-to-consumer genetic tests. Family history remains the most useful genetic 'test' for ADHD risk.