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Pediatrician by Tio Manolo

Wednesday, June 3, 2026 Edition XXXXXXXXXIV
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This Week in Pediatrics

FDA news in pediatrics: May 2026 | Contemporary Pediatrics

On May 29, 2026, the FDA approved Afrezza for children and adolescents aged 6 years and older with diabetes, making it the first rapid-acting inhaled insulin available for pediatric patients requiring mealtime insulin.

Hospitals See Diseases Resurge as Vaccinations Decline - The New York Times

Doctors nationwide are encountering more children with whooping cough, bacterial infections and other serious illnesses, as well as more adults refusing tetanus shots.

Precision Child Health: Transforming Pediatric Care - Hospital News

Wilson’s team is using machine learning algorithms on genetic and epigenetic data collected from multiple species to predict the impact of non-coding genetic variants observed in children with rare conditions. “With high-performance computing we can do analyses we’d only dream of...

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Research of the Day

Bedtime Screen Use and Sleep Quality in School-Age Children: Actigraphy Study

Using wrist actigraphy and sleep diaries, this study objectively measured sleep in 800 children ages 6-12 with varying bedtime screen habits. Screen use within 1 hour of bedtime significantly delayed sleep onset and reduced total sleep time.

Key findings: (1) 30-minute average delay in sleep onset with bedtime screens; (2) 45-minute reduction in total sleep time; (3) Blue light filtering partially but not fully mitigated effects.

🩺 What this means for your practice:

Recommend screen-free wind-down periods of 1+ hours before bed. Counsel families on device-free bedrooms. Address screen habits as part of sleep hygiene discussions.

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Popular Beliefs

Sugar makes children hyperactive

What the evidence shows: Multiple double-blind, placebo-controlled studies have found no significant effect of sugar on behavior or cognitive performance in children, even in those reportedly 'sensitive' to sugar. The perceived hyperactivity is often due to the context (parties, holidays) or parental expectations. However, limiting added sugars remains important for dental health and nutrition.

Shaving makes hair grow back thicker and darker

What the evidence shows: Shaving removes hair at the skin surface, leaving a blunt tip that may feel coarser as it grows out. However, it does not affect hair thickness, color, or growth rate. This is an optical illusion from the blunt vs. tapered hair shaft.

Eating carrots dramatically improves vision

What the evidence shows: While carrots contain vitamin A important for eye health, eating extra carrots won't improve normal vision or eliminate the need for glasses. Vitamin A deficiency can cause vision problems, but this is rare in developed countries with varied diets.

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Behaviors

Physical Activity and Academic Achievement: School-Based Intervention Study

This cluster RCT examined whether increasing physical activity during the school day improved academic outcomes in 3,500 elementary students. Schools were randomized to add 30 minutes of daily activity or continue standard curriculum.

Key findings: (1) Intervention students showed 15% improvement in reading scores; (2) Math scores improved 8%; (3) On-task behavior increased and disruptive behavior decreased. Benefits were greatest for students with ADHD symptoms.

🩺 What this means for your practice:

Advocate for physical activity in schools—it enhances rather than detracts from learning. Counsel families on the importance of daily active play for cognitive development, not just physical health.

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Genetics

Exon-Skipping Therapy for Duchenne Muscular Dystrophy: Expanded Approvals

FDA has approved additional exon-skipping therapies targeting previously untreatable Duchenne muscular dystrophy mutations. These antisense oligonucleotide treatments now cover 80% of DMD patients, slowing disease progression.

Key findings: (1) Treated patients maintain ambulation 2-4 years longer; (2) Cardiac and respiratory function also preserved; (3) Earlier treatment initiation correlates with better outcomes.

🩺 What this means for your practice:

Genetic testing to identify specific DMD mutation is essential for treatment planning. Refer to neuromuscular centers for evaluation. Treatment options continue to expand rapidly.

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Did You Know? Numbers & Statistics

84%
Infants ever breastfed in the US
CDC Breastfeeding Report Card, 2024
42%
High school students reporting persistent sadness or hopelessness
CDC YRBS, 2024
73%
Children 19-35 months with complete recommended vaccinations
CDC NIS, 2024
9.4%
Children ages 3-17 diagnosed with anxiety
CDC NHIS, 2024