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Pediatrician by Tio Manolo

Friday, June 5, 2026 Edition XXXXXXXXXVI
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This Week in Pediatrics

FDA news in pediatrics: May 2026 | Contemporary Pediatrics

On May 29, 2026, the FDA approved Afrezza for children and adolescents aged 6 years and older with diabetes, making it the first rapid-acting inhaled insulin available for pediatric patients requiring mealtime insulin.

Pediatrics - Medscape

Healthcare Strikes Ethical in Few Cases: Ethicist · Medscape Business of Medicine June 3, 2026 · Expert Witness Side Gigs: Good Pay, Rewarding Work · Medscape Medical News June 3, 2026 · ‘Something Died in Me’: Why Dedicated Doctors Quit Medicine · Medscape Medical News May 28, 2...

Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips

The FDA extended its review of adrabetadex for infantile-onset Niemann-Pick disease type C to November 17, 2026, after a major NDA amendment. ... UCLA researchers identified EPAC2 as a potential Fragile X syndrome treatment target after improving ...

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Research of the Day

Adolescent Vaping Cessation: Randomized Trial of Behavioral Interventions

This RCT compared three vaping cessation approaches in 1,200 adolescents: text-based support, in-person counseling, and combined intervention. Combined approach showed highest quit rates at 6-month follow-up.

Key findings: (1) 28% quit rate with combined intervention vs 15% text-only; (2) Nicotine dependence level predicted quit success; (3) Most adolescents wanted to quit but lacked support resources.

🩺 What this means for your practice:

Screen for vaping at every adolescent visit. Offer cessation resources proactively—most teens want to quit. Combine counseling with digital support for best outcomes.

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Popular Beliefs

Chocolate causes acne

What the evidence shows: The relationship between diet and acne is complex. Some studies suggest high-glycemic diets and dairy may worsen acne, but chocolate specifically has not been definitively proven to cause breakouts. Individual responses vary—advise patients to observe their own triggers.

Green mucus means bacterial infection requiring antibiotics

What the evidence shows: Mucus color changes naturally during viral infections and does not reliably distinguish viral from bacterial causes. Green/yellow mucus indicates immune cell activity, which occurs in both viral and bacterial infections. Antibiotics should be prescribed based on clinical criteria, not mucus color.

Vaccines cause autism

What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.

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Behaviors

Family Meal Frequency and Obesity Risk: Systematic Review and Meta-Analysis

This meta-analysis synthesized 45 studies examining the relationship between family meal frequency and childhood obesity. Children who shared regular family meals had significantly lower obesity risk and healthier eating patterns.

Key findings: (1) 3+ family meals/week associated with 12% lower overweight/obesity; (2) Higher fruit/vegetable intake and lower fast food consumption; (3) Protective effect independent of family structure or income.

🩺 What this means for your practice:

Encourage family meals as part of healthy lifestyle counseling. Even a few shared meals per week make a difference. Focus on the ritual and connection, not just nutrition.

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Genetics

Genetic Risk Screening for Type 1 Diabetes: Prevention Trial Update

Large-scale genetic screening of newborns identifies high-risk children for T1D prevention trials. Early results suggest immune modulation in high-risk children may delay or prevent onset of diabetes.

Key findings: (1) 5% of screened infants fall into high-risk category; (2) Early intervention delayed onset by average 3 years; (3) Screening acceptable to most families when explained appropriately.

🩺 What this means for your practice:

T1D prevention is moving from research to clinical reality. Stay updated on trial availability. For families with T1D history, genetic counseling and risk assessment may be appropriate for siblings.

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Did You Know? Numbers & Statistics

30%
Antibiotic prescriptions for children that are unnecessary
CDC, 2024
1 in 36
Children identified with Autism Spectrum Disorder in the US
CDC ADDM Network, 2024
38%
Children 6mo-17y completed COVID-19 primary series
CDC, 2024
33.4
SUID deaths per 100,000 live births
CDC, 2024