This Week in Pediatrics
FDA news in pediatrics: May 2026 | Contemporary Pediatrics
On May 29, 2026, the FDA approved Afrezza for children and adolescents aged 6 years and older with diabetes, making it the first rapid-acting inhaled insulin available for pediatric patients requiring mealtime insulin.
Pediatrics - Medscape
Medscape Medical News June 8, 2026 · Choosing a Journal: What Matters More Than Impact Factor? Medscape News Global June 8, 2026 View All · The Case for Screening Parents at the Pediatric Visit · Commentary June 5, 2026 · The parents’ mental health affects the child’s mental heal...
Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips
The FDA extended its review of adrabetadex for infantile-onset Niemann-Pick disease type C to November 17, 2026, after a major NDA amendment. ... UCLA researchers identified EPAC2 as a potential Fragile X syndrome treatment target after improving ...
Research of the Day
Iron Deficiency in Infancy and Long-Term Cognitive Outcomes: 10-Year Follow-Up
This prospective cohort followed children with iron deficiency anemia in infancy through age 10, comparing cognitive outcomes to iron-sufficient peers. Despite iron repletion in infancy, children with early anemia showed persistent differences in executive function and spatial memory.
Key findings: (1) Early iron deficiency associated with lower scores on math and reading assessments; (2) Differences in brain structure observed on MRI at age 10; (3) Duration of deficiency correlated with magnitude of effect.
Emphasize prevention through dietary counseling and appropriate screening. Iron-rich complementary foods should be introduced at 6 months. Consider iron supplementation in high-risk populations.
Popular Beliefs
Too many vaccines overwhelm a child's immune system
What the evidence shows: Children's immune systems handle vastly more antigens daily from the environment than from vaccines. Today's vaccines contain far fewer antigens than older versions despite protecting against more diseases. Studies show no increased infection rates in vaccinated children—vaccines strengthen, not weaken, immunity.
Organic food is significantly more nutritious
What the evidence shows: Organic foods have lower pesticide residues, but studies show minimal nutritional differences compared to conventional foods. What matters most for health is eating a variety of fruits and vegetables, whether organic or conventional.
Sugar makes children hyperactive
What the evidence shows: Multiple double-blind, placebo-controlled studies have found no significant effect of sugar on behavior or cognitive performance in children, even in those reportedly 'sensitive' to sugar. The perceived hyperactivity is often due to the context (parties, holidays) or parental expectations. However, limiting added sugars remains important for dental health and nutrition.
Behaviors
Secondhand Smoke Exposure and Cognitive Development: Cohort Study
This cohort study measured cotinine levels and cognitive outcomes in 2,000 children at multiple time points. Even low-level secondhand smoke exposure was associated with measurable effects on attention and working memory.
Key findings: (1) Detectable cotinine associated with 5-point IQ difference; (2) Higher rates of learning difficulties; (3) No safe threshold identified—any exposure had measurable effects.
Screen for smoke exposure at well visits. Counsel caregivers that even 'smoking outside' may not fully protect children. Connect families with smoking cessation resources.
Genetics
Genetic Predictors of Peanut Allergy Persistence
Genome-wide association study identifies genetic variants associated with peanut allergy persistence versus resolution. Children with certain variants are more likely to outgrow their allergy, informing timing of oral food challenges.
Key findings: (1) 4 genetic variants strongly associated with persistence; (2) Genetic testing could reduce unnecessary avoidance and challenges; (3) Environmental factors remain important in allergy development.
Genetic testing may soon help predict which children will outgrow allergies. For now, continue regular reassessment with IgE testing and oral challenges as clinically indicated.