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Pediatrician by Tio Manolo

Tuesday, June 23, 2026 Edition XXXXXXXXXXXIV
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This Week in Pediatrics

Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips

ByMorgan Ebert, Executive Editor,Kevin Kaiserman, MD ... New ADA 2026 analyses show Afrezza delivered comparable glycemic control, favorable safety, and higher treatment satisfaction in youth.

Type 2 Diabetes Study Finds What's Stealing Adolescents' Sleep

Hear from researchers as they briefly explain one of their recent studies and how it could improve healthcare. In this installment, we highlight how vaccinated and unvaccinated children's bodies respond differently to a flu infection and what's costing adolescents with ...

AI helped diagnose 18 children whose rare diseases had stumped doctors

The findings, announced Thursday in the New England Journal of Medicine’s AI-focused publication, NEJM AI, show that OpenAI’s o3 Deep Research model helped clarify 18 diagnoses for children who had struggled to find causes for their illnesses and symptoms.

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Research of the Day

Return to Sport After Pediatric Concussion: Age-Modified Protocols

This multi-site study evaluated age-specific return-to-sport protocols following concussion in 2,500 young athletes ages 8-18. Younger children required longer recovery periods, challenging one-size-fits-all protocols.

Key findings: (1) Median recovery 21 days for ages 8-12 vs 14 days for teens; (2) Early return to sport associated with prolonged symptoms; (3) Symptom-limited activity during recovery improved outcomes.

🩺 What this means for your practice:

Use age-appropriate return protocols. Younger athletes need more conservative management. Emphasize symptom-limited activity and complete recovery before returning to full sport.

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Popular Beliefs

Sugar makes children hyperactive

What the evidence shows: Multiple double-blind, placebo-controlled studies have found no significant effect of sugar on behavior or cognitive performance in children, even in those reportedly 'sensitive' to sugar. The perceived hyperactivity is often due to the context (parties, holidays) or parental expectations. However, limiting added sugars remains important for dental health and nutrition.

Warm milk helps children sleep

What the evidence shows: While milk contains tryptophan (a sleep-promoting amino acid), the amount is modest. Any sleep benefit likely comes from the comforting ritual and warmth rather than pharmacologic effect. A consistent bedtime routine matters more than any single component.

Starve a fever, feed a cold

What the evidence shows: Neither fevers nor colds benefit from restricting food. Both conditions increase metabolic demands, and adequate nutrition supports immune function. Encourage normal eating as tolerated and emphasize hydration with any illness.

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Behaviors

Musical Training and Brain Development in Children: Longitudinal Neuroimaging Study

This 3-year study compared brain development in children receiving musical instrument training versus those doing sports or no organized activity. Music training was associated with enhanced auditory processing, motor coordination, and executive function networks.

Key findings: (1) Increased cortical thickness in auditory and motor regions; (2) Better performance on working memory and attention tasks; (3) Benefits correlated with practice duration.

🩺 What this means for your practice:

Music education offers cognitive benefits beyond artistic development. When families ask about extracurriculars, mention music as a brain-healthy option. Benefits appear even with modest practice time.

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Genetics

CFTR Modulator Therapy in Young Children: Expansion to Additional Mutations

New clinical trial data supports expanding CFTR modulator therapy to children as young as 1 year with various CFTR mutations. Early treatment initiation shows benefits in lung function preservation and nutritional status, with excellent safety profile.

Key findings: (1) 85% of CF patients now eligible for modulator therapy; (2) Early treatment prevents rather than reverses lung damage; (3) Growth parameters improved in treated toddlers.

🩺 What this means for your practice:

Refer CF patients promptly for genetic classification and modulator eligibility assessment. The treatment landscape has transformed—many children can now expect near-normal life expectancy with appropriate therapy.

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Did You Know? Numbers & Statistics

35+
Conditions screened on most state newborn screening panels
HHS, 2024
10%
High school students reporting current e-cigarette use
CDC YRBS, 2024
24%
Children meeting 60 min/day physical activity guideline
CDC YRBS, 2024
13%
Children diagnosed with eczema/atopic dermatitis
CDC NHIS, 2024