This Week in Pediatrics
FDA updates in pediatric care: Q2 2026 recap | Contemporary Pediatrics
On April 22, 2026, the FDA approved dupilumab (Dupixent; Regeneron/Sanofi) for chronic spontaneous urticaria (CSU) in children aged 2 to 11 years who remain symptomatic despite H1-antihistamine therapy.
‘Paradigm-shifting’ treatment for pediatric diabetes cleared by FDA | Yale News
Yale’s Kevan Herold was the senior investigator on a clinical trial which showed that the drug teplizumab — recently approved for pediatric patients with Stage 3 Type 1 diabetes — delays the progression of the disease.
Top 5 pediatric health headlines you missed in January 2026 | Contemporary Pediatrics
Under the revised schedule, several vaccines—including those for hepatitis A, hepatitis B, respiratory syncytial virus, influenza, rotavirus, and meningococcal disease—are no longer routinely recommended for all children.
Research of the Day
Inhaled Corticosteroid Adherence in Minority Children: Community Health Worker Intervention
This RCT evaluated community health worker (CHW) home visits to improve inhaled corticosteroid adherence in 400 minority children with persistent asthma. CHW intervention nearly doubled medication adherence rates.
Key findings: (1) Adherence improved from 45% to 82% in intervention group; (2) 50% reduction in asthma-related ED visits; (3) Culturally tailored education more effective than standard approach.
Consider CHW programs or similar support for families struggling with asthma medication adherence. Address social determinants and provide culturally appropriate education.
Popular Beliefs
Children outgrow ADHD
What the evidence shows: While symptoms often change with age, approximately 60% of children with ADHD continue to have symptoms into adulthood. Hyperactivity typically decreases, but inattention and impulsivity often persist. Ongoing monitoring and treatment adjustment is important across the lifespan.
Cracking knuckles causes arthritis
What the evidence shows: Studies comparing habitual knuckle-crackers to non-crackers found no increased arthritis risk. The cracking sound is from gas bubble release in synovial fluid. The main consequence may be reduced grip strength and annoyed family members.
Vaccines cause autism
What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.
Behaviors
Growth Mindset and Academic Resilience in Middle School
This school-based intervention taught growth mindset principles to 4,000 middle schoolers. Students who internalized growth mindset showed improved grades, greater persistence, and reduced anxiety around academic challenges.
Key findings: (1) 0.3 GPA improvement in intervention group; (2) 25% reduction in test anxiety; (3) Effects largest for initially low-performing students. Teacher reinforcement of messages enhanced effects.
Praise effort over ability when discussing academics with patients. Encourage families to use growth mindset language. Struggle is part of learning, not a sign of inability.
Genetics
Genetic Risk Screening for Type 1 Diabetes: Prevention Trial Update
Large-scale genetic screening of newborns identifies high-risk children for T1D prevention trials. Early results suggest immune modulation in high-risk children may delay or prevent onset of diabetes.
Key findings: (1) 5% of screened infants fall into high-risk category; (2) Early intervention delayed onset by average 3 years; (3) Screening acceptable to most families when explained appropriately.
T1D prevention is moving from research to clinical reality. Stay updated on trial availability. For families with T1D history, genetic counseling and risk assessment may be appropriate for siblings.