This Week in Pediatrics
FDA updates in pediatric care: Q2 2026 recap | Contemporary Pediatrics
On April 22, 2026, the FDA approved dupilumab (Dupixent; Regeneron/Sanofi) for chronic spontaneous urticaria (CSU) in children aged 2 to 11 years who remain symptomatic despite H1-antihistamine therapy.
Pediatric clinical trial update: Q2 2026 | Contemporary Pediatrics
The findings further support the long-term efficacy and tolerability of TransCon CNP, which received FDA approval in February 2026 for pediatric patients aged 2 years and older with achondroplasia and open epiphyses.
Top 5 pediatric health headlines you missed in January 2026 | Contemporary Pediatrics
Under the revised schedule, several vaccines—including those for hepatitis A, hepatitis B, respiratory syncytial virus, influenza, rotavirus, and meningococcal disease—are no longer routinely recommended for all children.
Research of the Day
Duration of Breastfeeding and Childhood Obesity Risk: Meta-Analysis of 150 Cohort Studies
This comprehensive meta-analysis synthesized data from 150 cohort studies involving over 2.5 million children to examine the relationship between breastfeeding duration and obesity risk. Children breastfed for 6+ months showed a 22% reduction in obesity risk at ages 5-10 compared to never-breastfed children.
Key findings: (1) Each additional month of breastfeeding associated with 3% lower obesity odds; (2) Effects persisted after adjusting for socioeconomic status and maternal BMI; (3) Exclusive breastfeeding showed stronger effects than mixed feeding.
These findings strengthen breastfeeding support recommendations. Counsel expectant parents on breastfeeding benefits, ensure access to lactation support, and address barriers to continued breastfeeding.
Popular Beliefs
Chocolate causes acne
What the evidence shows: The relationship between diet and acne is complex. Some studies suggest high-glycemic diets and dairy may worsen acne, but chocolate specifically has not been definitively proven to cause breakouts. Individual responses vary—advise patients to observe their own triggers.
Shaving makes hair grow back thicker and darker
What the evidence shows: Shaving removes hair at the skin surface, leaving a blunt tip that may feel coarser as it grows out. However, it does not affect hair thickness, color, or growth rate. This is an optical illusion from the blunt vs. tapered hair shaft.
Starve a fever, feed a cold
What the evidence shows: Neither fevers nor colds benefit from restricting food. Both conditions increase metabolic demands, and adequate nutrition supports immune function. Encourage normal eating as tolerated and emphasize hydration with any illness.
Behaviors
Green Space Exposure and Mental Health in Urban Adolescents
This longitudinal study followed 5,000 urban adolescents over 4 years, using GPS tracking to measure green space exposure. Greater exposure to parks and nature was associated with lower rates of depression and anxiety, independent of socioeconomic factors.
Key findings: (1) 20% lower depression risk with daily green space exposure; (2) Benefits dose-dependent—more exposure meant better outcomes; (3) Active use (sports, walking) showed greater benefits than passive exposure.
Encourage outdoor time as part of mental health promotion. For families in urban areas, identify nearby parks and green spaces. Nature exposure is an accessible, cost-effective mental health intervention.
Genetics
Exon-Skipping Therapy for Duchenne Muscular Dystrophy: Expanded Approvals
FDA has approved additional exon-skipping therapies targeting previously untreatable Duchenne muscular dystrophy mutations. These antisense oligonucleotide treatments now cover 80% of DMD patients, slowing disease progression.
Key findings: (1) Treated patients maintain ambulation 2-4 years longer; (2) Cardiac and respiratory function also preserved; (3) Earlier treatment initiation correlates with better outcomes.
Genetic testing to identify specific DMD mutation is essential for treatment planning. Refer to neuromuscular centers for evaluation. Treatment options continue to expand rapidly.