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Pediatrician by Tio Manolo

Saturday, July 4, 2026 Edition XXXXXXXXXXXXV
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This Week in Pediatrics

FDA news in pediatrics: June 2026 | Contemporary Pediatrics

On June 10, 2026, the FDA approved expanded indications for tocilizumab-bavi (Tofidence), adding severe or life-threatening CAR T-cell–induced cytokine release syndrome and hospitalized COVID-19 in patients aged 2 years and older, broadening ...

Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips

... New AAP guidance recommends age-specific iron deficiency screening, updated ferritin thresholds, and simplified treatment strategies for children. ... FDA approved risankizumab for children 6 and older with plaque psoriasis or psoriatic ...

Pediatric clinical trial update: Q2 2026 | Contemporary Pediatrics

The findings further support the long-term efficacy and tolerability of TransCon CNP, which received FDA approval in February 2026 for pediatric patients aged 2 years and older with achondroplasia and open epiphyses.

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Research of the Day

Adolescent Vaping Cessation: Randomized Trial of Behavioral Interventions

This RCT compared three vaping cessation approaches in 1,200 adolescents: text-based support, in-person counseling, and combined intervention. Combined approach showed highest quit rates at 6-month follow-up.

Key findings: (1) 28% quit rate with combined intervention vs 15% text-only; (2) Nicotine dependence level predicted quit success; (3) Most adolescents wanted to quit but lacked support resources.

🩺 What this means for your practice:

Screen for vaping at every adolescent visit. Offer cessation resources proactively—most teens want to quit. Combine counseling with digital support for best outcomes.

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Popular Beliefs

ADD/ADHD is caused by poor parenting or too much sugar

What the evidence shows: ADHD has strong genetic and neurobiological components. While environment can influence symptom severity, poor parenting and diet do not cause ADHD. Evidence-based treatments include behavioral therapy and, when appropriate, medication. Blaming parents is harmful and delays effective intervention.

Vaccines cause autism

What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.

Eating carrots dramatically improves vision

What the evidence shows: While carrots contain vitamin A important for eye health, eating extra carrots won't improve normal vision or eliminate the need for glasses. Vitamin A deficiency can cause vision problems, but this is rare in developed countries with varied diets.

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Behaviors

Musical Training and Brain Development in Children: Longitudinal Neuroimaging Study

This 3-year study compared brain development in children receiving musical instrument training versus those doing sports or no organized activity. Music training was associated with enhanced auditory processing, motor coordination, and executive function networks.

Key findings: (1) Increased cortical thickness in auditory and motor regions; (2) Better performance on working memory and attention tasks; (3) Benefits correlated with practice duration.

🩺 What this means for your practice:

Music education offers cognitive benefits beyond artistic development. When families ask about extracurriculars, mention music as a brain-healthy option. Benefits appear even with modest practice time.

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Genetics

Gene Therapy Shows Promise for Spinal Muscular Atrophy Type 1

Long-term follow-up data from the Phase 3 clinical trial of onasemnogene abeparvovec gene therapy reveals sustained motor milestone achievements in children with SMA Type 1 treated before 6 months of age. At 5-year follow-up, 94% of early-treated patients maintained the ability to sit independently, and 68% achieved independent walking—outcomes historically unprecedented in untreated SMA Type 1.

The study also reports on safety outcomes, with no new treatment-related serious adverse events emerging after year 2. These results strengthen the case for newborn screening and early intervention in SMA.

🩺 What this means for your practice:

This data reinforces the critical importance of early diagnosis and treatment in SMA. Support newborn screening initiatives in your state. For families with SMA history, discuss carrier testing and ensure rapid referral to neuromuscular specialists if symptoms arise.

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Did You Know? Numbers & Statistics

8%
Children with food allergies
CDC NCHS, 2024
84%
Infants ever breastfed in the US
CDC Breastfeeding Report Card, 2024
61%
Adolescents 13-17 with complete HPV vaccination
CDC NIS-Teen, 2024
22%
High school students who considered suicide
CDC YRBS, 2024