This Week in Pediatrics
FDA news in pediatrics: June 2026 | Contemporary Pediatrics
On June 10, 2026, the FDA approved expanded indications for tocilizumab-bavi (Tofidence), adding severe or life-threatening CAR T-cell–induced cytokine release syndrome and hospitalized COVID-19 in patients aged 2 years and older, broadening ...
Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips
... New AAP guidance recommends age-specific iron deficiency screening, updated ferritin thresholds, and simplified treatment strategies for children. ... FDA approved risankizumab for children 6 and older with plaque psoriasis or psoriatic ...
Pediatric clinical trial update: Q2 2026 | Contemporary Pediatrics
The findings further support the long-term efficacy and tolerability of TransCon CNP, which received FDA approval in February 2026 for pediatric patients aged 2 years and older with achondroplasia and open epiphyses.
Research of the Day
Social Media Use and Depression in Early Adolescence: Longitudinal Analysis
This 3-year longitudinal study followed 6,500 adolescents ages 12-15, tracking social media use patterns and mental health outcomes. High social media use (>3 hours/day) was associated with increased depression risk, though the relationship was bidirectional.
Key findings: (1) 35% increased odds of elevated depressive symptoms with high use; (2) Social comparison and cyberbullying mediated the relationship; (3) Active use (creating content) showed smaller associations than passive consumption.
Screen for problematic social media use during well visits. Counsel families on media limits, encourage active over passive use, and discuss warning signs of cyberbullying and unhealthy comparison.
Popular Beliefs
Teething causes high fevers and diarrhea
What the evidence shows: While teething may cause mild symptoms (gum irritation, drooling, slight temperature elevation), it does not cause high fever (>102°F/38.9°C) or diarrhea. These symptoms should prompt evaluation for other causes. Attributing significant illness to teething may delay diagnosis of serious conditions.
Sugar makes children hyperactive
What the evidence shows: Multiple double-blind, placebo-controlled studies have found no significant effect of sugar on behavior or cognitive performance in children, even in those reportedly 'sensitive' to sugar. The perceived hyperactivity is often due to the context (parties, holidays) or parental expectations. However, limiting added sugars remains important for dental health and nutrition.
Organic food is significantly more nutritious
What the evidence shows: Organic foods have lower pesticide residues, but studies show minimal nutritional differences compared to conventional foods. What matters most for health is eating a variety of fruits and vegetables, whether organic or conventional.
Behaviors
Screen Time and Executive Function in Preschoolers: A Longitudinal Analysis
This prospective cohort study followed 850 children from ages 2 to 5 years, examining the relationship between screen time exposure and executive function development. Researchers used validated parent-report measures and direct assessments of working memory, inhibitory control, and cognitive flexibility.
Children with more than 2 hours of daily screen time at age 2 showed lower scores on executive function measures at age 5. Notably, the type of screen content mattered—educational programming showed smaller associations than passive entertainment viewing. Joint parent-child viewing partially mitigated negative effects.
These findings support counseling families on the AAP recommendation of less than 1 hour per day of high-quality programming for children 2-5 years. Emphasize co-viewing and educational content when screens are used. Executive function is crucial for school readiness and later academic success.
Genetics
CFTR Modulator Therapy in Young Children: Expansion to Additional Mutations
New clinical trial data supports expanding CFTR modulator therapy to children as young as 1 year with various CFTR mutations. Early treatment initiation shows benefits in lung function preservation and nutritional status, with excellent safety profile.
Key findings: (1) 85% of CF patients now eligible for modulator therapy; (2) Early treatment prevents rather than reverses lung damage; (3) Growth parameters improved in treated toddlers.
Refer CF patients promptly for genetic classification and modulator eligibility assessment. The treatment landscape has transformed—many children can now expect near-normal life expectancy with appropriate therapy.