This Week in Pediatrics
JAMA Pediatrics – The Science of Child and Adolescent Health
Explore the latest in child health including food and nutrition, Kawasaki disease and C difficile, effects of media, and more. Formerly Archives of Pediatrics.
FDA Expands Risankizumab Approval to Pediatric Plaque Psoriasis, Active PsA | AJMC
"These clinical responses, combined ... School of Medicine, said in a news release.1 ... Skyrizi (risankizumab-rzaa) now FDA approved for pediatric use in psoriatic disease....
2026 Pediatrics in Review | shopAAP
Pediatrics in Review (PIR) helps keep me up to date and informed. It’s my go-to source to succinctly answer general clinical questions. Andrea Branch MD, FAAP · I consider PIR to be the Educational Heart of our Profession! Laura Heimback-Graham, MD, FAAP · PIR is an easy and inte...
Research of the Day
Probiotics for Infantile Colic: Randomized Controlled Trial of L. reuteri
This double-blind RCT enrolled 400 breastfed infants with colic to evaluate Lactobacillus reuteri supplementation. Infants receiving the probiotic showed significantly reduced crying time compared to placebo, with effects observed within 7 days of treatment initiation.
Key findings: (1) Mean crying time reduced by 51 minutes/day at 21 days; (2) 73% of treatment group had crying <3 hours/day vs 36% placebo; (3) No adverse events reported. Effect was specific to breastfed infants.
L. reuteri may be considered for breastfed infants with colic after excluding other causes. This is one of several evidence-based interventions alongside feeding adjustments, carrying techniques, and parental support.
Popular Beliefs
Vaccines cause autism
What the evidence shows: This thoroughly debunked claim originated from a fraudulent 1998 study. Multiple large-scale studies involving millions of children have found no association between vaccines and autism. The original study was retracted and its author lost his medical license. Vaccines are safe and essential.
Starve a fever, feed a cold
What the evidence shows: Neither fevers nor colds benefit from restricting food. Both conditions increase metabolic demands, and adequate nutrition supports immune function. Encourage normal eating as tolerated and emphasize hydration with any illness.
Eating carrots dramatically improves vision
What the evidence shows: While carrots contain vitamin A important for eye health, eating extra carrots won't improve normal vision or eliminate the need for glasses. Vitamin A deficiency can cause vision problems, but this is rare in developed countries with varied diets.
Behaviors
Sleep Schedule Consistency and ADHD Symptoms: Intervention Study
This intervention study examined whether consistent sleep schedules improved ADHD symptoms in 150 children ages 6-12. Families implemented strict bed/wake times for 8 weeks while tracking symptoms and sleep.
Key findings: (1) Consistent sleep reduced inattention symptoms by 25%; (2) Bedtime resistance decreased significantly; (3) Effects comparable to some medication responses. Weekend sleep consistency was particularly important.
Before escalating ADHD treatment, optimize sleep hygiene. Consistent bed/wake times (including weekends) can meaningfully improve symptoms. This is a low-risk intervention all families can implement.
Genetics
Newborn Screening: Recommended Uniform Screening Panel Updates
The Recommended Uniform Screening Panel (RUSP) has been updated to include three additional conditions: Pompe disease, MPS I, and X-linked adrenoleukodystrophy. States are implementing expanded screening with early treatment implications.
Key findings: (1) Early identification allows treatment before symptom onset; (2) Cost-effectiveness demonstrated for new conditions; (3) Primary care providers need to understand screening results and follow-up.
Know your state's newborn screening panel. Ensure timely follow-up of abnormal screens. Early treatment dramatically improves outcomes for many of these conditions.