This Week in Pediatrics
FDA news in pediatrics: August 2026 | Contemporary Pediatrics
On August 19, 2026, the FDA accepted Teva's New Drug Application and granted priority review to ecopipam, a first-in-class selective dopamine D1 receptor antagonist, for pediatric Tourette syndrome, with a target action date in late Q1 2027.
Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips
Chronic skin conditions linked to bullying, depression, and suicide risk in children, adolescents · Chronic pediatric skin disorders cause significant stigma, bullying, depression, and suicide risk—conditions often underrecognized and ...
JAMA Pediatrics – The Science of Child and Adolescent Health
Explore the latest in child health including food and nutrition, Kawasaki disease and C difficile, effects of media, and more. Formerly Archives of
Research of the Day
Delayed Epinephrine Administration in Pediatric Anaphylaxis: Multi-Center Analysis
This multi-center retrospective study analyzed 2,800 pediatric anaphylaxis cases across 12 children's hospitals. Delayed epinephrine administration (>15 minutes from symptom onset) occurred in 42% of cases and was associated with increased risk of severe outcomes and biphasic reactions.
Key findings: (1) Delayed epinephrine associated with 3.2x increased odds of hospitalization; (2) Food-induced reactions most likely to have delayed treatment; (3) Many families cited fear of injection or uncertainty about symptoms as reasons for delay.
Reinforce epinephrine-first messaging for anaphylaxis. Ensure families can recognize symptoms and use auto-injectors confidently. Consider demonstration at every visit for patients with prescribed epinephrine.
Popular Beliefs
The flu shot can give you the flu
What the evidence shows: Flu vaccines contain inactivated virus or viral proteins that cannot cause influenza infection. Some people experience mild side effects (sore arm, low-grade fever) that mimic illness. It takes 2 weeks for protection to develop, so some may get infected before the vaccine works.
Warm milk helps children sleep
What the evidence shows: While milk contains tryptophan (a sleep-promoting amino acid), the amount is modest. Any sleep benefit likely comes from the comforting ritual and warmth rather than pharmacologic effect. A consistent bedtime routine matters more than any single component.
ADD/ADHD is caused by poor parenting or too much sugar
What the evidence shows: ADHD has strong genetic and neurobiological components. While environment can influence symptom severity, poor parenting and diet do not cause ADHD. Evidence-based treatments include behavioral therapy and, when appropriate, medication. Blaming parents is harmful and delays effective intervention.
Behaviors
Early Pet Exposure and Immune Development: Birth Cohort Study
This birth cohort followed 1,200 children from birth to age 5, comparing immune development and allergy rates in homes with and without pets. Early pet exposure was associated with reduced allergy risk and altered gut microbiome.
Key findings: (1) 30% lower allergic sensitization with dog exposure in first year; (2) Cat exposure showed similar but smaller effects; (3) Microbiome diversity increased in pet-exposed children.
Reassure families that pet exposure during infancy may actually protect against allergies. For families without pets, don't specifically recommend getting one, but dispel the myth that pets must be removed to prevent allergies.
Genetics
CFTR Modulator Therapy in Young Children: Expansion to Additional Mutations
New clinical trial data supports expanding CFTR modulator therapy to children as young as 1 year with various CFTR mutations. Early treatment initiation shows benefits in lung function preservation and nutritional status, with excellent safety profile.
Key findings: (1) 85% of CF patients now eligible for modulator therapy; (2) Early treatment prevents rather than reverses lung damage; (3) Growth parameters improved in treated toddlers.
Refer CF patients promptly for genetic classification and modulator eligibility assessment. The treatment landscape has transformed—many children can now expect near-normal life expectancy with appropriate therapy.