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Pediatrician by Tio Manolo

Monday, October 26, 2026 — Edition XXXXXXXXXXXXXXXXXXXXXXXIX
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This Week in Pediatrics

FDA news in pediatrics: June 2026 | Contemporary Pediatrics

Keisha L. Gibson, MD, MPH, discusses the FDA approval of Gazyva for childhood-onset INS and its implications for relapse prevention and pediatric care. ... Topical botanical Cinainu earned FDA Breakthrough Therapy status for AA in patients aged ...

Contemporary Pediatrics – Clinical News & Pediatrician Practice Tips

Get back-to-school pediatric guidance ... watch this year. ... Court fight over CDC 2026 childhood vaccine schedule shifts shots to shared decision-making; experts warn lower uptake for Hep A, B, flu, COVID....

Top 5 pediatric health headlines you missed in August 2026 | Contemporary Pediatrics

Proposed legislation establishing ... PhD. The Sunshine Protection Act, which passed the US House of Representatives in July 2026 and awaits Senate action, would eliminate the annual return to Standard Time....

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Research of the Day

Early Antibiotic Exposure and Neurodevelopmental Outcomes: A Population-Based Cohort Study

This large population-based cohort study examined over 1.2 million children to investigate the association between antibiotic exposure in the first year of life and subsequent neurodevelopmental outcomes. The researchers found a modest but statistically significant association between early broad-spectrum antibiotic use and increased risk of ADHD and autism spectrum disorder diagnoses, though the absolute risk increase remained small.

Key findings include: (1) Children exposed to antibiotics in the first year had a 12% increased relative risk of ADHD diagnosis; (2) The association was stronger with repeated courses of broad-spectrum antibiotics; (3) The effect persisted after adjusting for maternal infections and other confounders.

🩺 What this means for your practice:

While the study shows an association, causation is not established. The findings support judicious antibiotic use in infants—prescribing when clinically indicated, but avoiding unnecessary courses.

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Popular Beliefs

Reading to babies is pointless—they don't understand

What the evidence shows: Research consistently demonstrates that reading to infants from birth supports language development, vocabulary acquisition, and later literacy skills. Even before understanding words, babies benefit from hearing language patterns, rhythm, and the bonding experience. The AAP recommends reading aloud beginning in infancy.

Cold weather causes colds

What the evidence shows: Colds are caused by viruses, not cold temperatures. The association exists because people spend more time indoors in close proximity during winter, facilitating viral transmission. Additionally, dry indoor air may impair mucosal barriers. Hand hygiene and avoiding sick contacts are the real prevention strategies.

Children outgrow ADHD

What the evidence shows: While symptoms often change with age, approximately 60% of children with ADHD continue to have symptoms into adulthood. Hyperactivity typically decreases, but inattention and impulsivity often persist. Ongoing monitoring and treatment adjustment is important across the lifespan.

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Behaviors

Physical Activity and Academic Achievement: School-Based Intervention Study

This cluster RCT examined whether increasing physical activity during the school day improved academic outcomes in 3,500 elementary students. Schools were randomized to add 30 minutes of daily activity or continue standard curriculum.

Key findings: (1) Intervention students showed 15% improvement in reading scores; (2) Math scores improved 8%; (3) On-task behavior increased and disruptive behavior decreased. Benefits were greatest for students with ADHD symptoms.

🩺 What this means for your practice:

Advocate for physical activity in schools—it enhances rather than detracts from learning. Counsel families on the importance of daily active play for cognitive development, not just physical health.

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Genetics

Gene Therapy Shows Promise for Spinal Muscular Atrophy Type 1

Long-term follow-up data from the Phase 3 clinical trial of onasemnogene abeparvovec gene therapy reveals sustained motor milestone achievements in children with SMA Type 1 treated before 6 months of age. At 5-year follow-up, 94% of early-treated patients maintained the ability to sit independently, and 68% achieved independent walking—outcomes historically unprecedented in untreated SMA Type 1.

The study also reports on safety outcomes, with no new treatment-related serious adverse events emerging after year 2. These results strengthen the case for newborn screening and early intervention in SMA.

🩺 What this means for your practice:

This data reinforces the critical importance of early diagnosis and treatment in SMA. Support newborn screening initiatives in your state. For families with SMA history, discuss carrier testing and ensure rapid referral to neuromuscular specialists if symptoms arise.

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Did You Know? Numbers & Statistics

24%
Children meeting 60 min/day physical activity guideline
CDC YRBS, 2024
1 in 36
Children identified with Autism Spectrum Disorder in the US
CDC ADDM Network, 2024
9.8%
Children ages 3-17 diagnosed with ADHD
CDC NHIS, 2024
5.4M
Children under 18 with asthma in the United States
CDC, 2024